RXi Pharmaceuticals (NASDAQ: RXII) shares are up more than 38% this morning after the company said it has been granted a patent by the Japan Patent Office for the composition of matter of sd-rxRNAs targeting connective tissue growth factor for the treatment or prevention of fibrotic disorders. Fibrotic disorders covered include, but are not limited to, skin fibrosis and proliferative retinopathy. This patent includes RXI-109, the company’s lead clinical candidate, which is currently being evaluated in phase 2 clinical trials. The patent will expire in 2031. “The granting of this patent in Japan further strengthens RXi’s intellectual property estate for future commercial and regional business development opportunities for RXI-109,” Chief Development Officer Pamela Pavco, Ph.D., stated in the news release.
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About RXi Pharmaceuticals
RXi Pharmaceuticals Corporation (NASDAQ: RXII) is a clinical-stage company developing innovative therapeutics that address significant unmet medical needs. Building on the pioneering discovery of RNAi, scientists at RXi have harnessed the naturally occurring RNAi process which has the ability to “silence” or down-regulate the expression of a specific gene that may be overexpressed in a disease condition. RXi developed a robust RNAi therapeutic platform including self-delivering RNA (sd-rxRNA®) compounds, that have the ability to highly selectively block the expression of any target in the genome, thus providing applicability to many therapeutic areas. The company’s current programs include dermatology, ophthalmology and cell-based immunotherapy. RXi’s extensive patent portfolio provides for multiple product and business development opportunities across a broad spectrum of therapeutic areas and it actively pursues research collaborations, partnering and out-licensing opportunities with academia and pharmaceutical companies. Additional information may be found on the company’s website, www.rxipharma.com.
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