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NetworkNewsBreaks – OncoSec’s (NASDAQ: ONCS) ImmunoPulse® IL-12 Receives Fast Track Designation to Treat Metastatic Melanoma

Company: OncoSec Medical, Inc. (ONCS)
Category: Stock Spotlights

OncoSec Medical (NASDAQ: ONCS) has received Fast Track designation from the U.S. Food and Drug Administration (FDA) for its ImmunoPulse® IL-12, a potentially first-in-class, Intratumoral anti-cancer gene therapy that expresses interleukin-12 (IL-12) for the treatment of metastatic melanoma, following progression on pembrolizumab or nivolumab. The company this morning announced that this designation permits frequent communications and meetings with the FDA, providing opportunity for the upcoming phase 2b PISCES clinical trial of ImmunoPulse® IL-12 in combination with an intravenous anti-PD-1 antibody. The clinical trial is planned to initiate in the first half of 2017. “With the recent presentation of our interim data from our ongoing combination study with pembrolizumab in patients predicted not to respond to single-agent anti-PD-1 therapy, we are increasingly confident in ImmunoPulse® IL-12 to potentially convert ‘cold’ tumors to ‘hot’ tumors to effectively and safely improve the response rates of these patients,” president and CEO Punit Dhillon stated in the news release.

To view the full press release, visit: http://nnw.fm/6eR0u

About OncoSec Medical

OncoSec is a biotechnology company developing DNA-based intratumoral immunotherapies with an investigational technology, ImmunoPulse®, for the treatment of cancer. ImmunoPulse® is designed to enhance the local delivery and uptake of DNA-based immune-targeting agents, such as IL-12. In phase I and II clinical trials, ImmunoPulse® IL-12 has demonstrated a favorable safety profile and evidence of anti-tumor activity in the treatment of various solid tumors as well as a systemic immune response. OncoSec’s lead program, ImmunoPulse® IL-12, is currently in clinical development for several indications, including metastatic melanoma and triple-negative breast cancer. The program’s current focus is on the significant unmet medical need in patients with melanoma who are refractory or non-responsive to anti-PD-1/PD-L1 therapies. In addition to ImmunoPulse® IL-12, the Company is also identifying and developing new immune-targeting agents for use with the ImmunoPulse® platform. For more information, please visit www.oncosec.com.

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