Ocera Therapeutics (NASDAQ: OCRX) is focused on the development of OCR-002 (ornithine phenylacetate) to treat hyperammonemia and subsequent hepatic encephalopathy (HE). An estimated eight million people in the U.S. suffer from chronic liver disease and approximately one million suffer from liver cirrhosis. HE is a debilitating and progressive complication of liver cirrhosis or liver failure marked by mental changes including confusion, impaired motor skills, and disorientation. Severe HE can cause stupor, coma and even death. Currently, there are no drug treatments that can be given intravenously to hospitalized patients with acute HE.
To learn more visit www.ocerainc.com
About Ocera
Ocera Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of OCR-002 (ornithine phenylacetate) in both intravenous and oral formulations. OCR-002 is an ammonia scavenger and has been granted orphan drug designation and Fast Track status by the U.S. Food and Drug Administration (FDA) for the treatment of hyperammonemia and resultant hepatic encephalopathy (HE) in patients with acute liver failure and acute-on-chronic liver disease. Ocera’s clinical development program also includes evaluation of orally-available OCR-002 in an ongoing Phase 1 study in patients with cirrhosis as a chronic use option to maintain remission of HE. Results of part one of this study are expected to be published by the end of 2016 with part two expected to commence in the first half of 2017.
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