More than 34 million people have died from HIV since it was first discovered in 1981, according to Healthline (http://nnw.fm/i9ptS). Although there is no known cure for the disease, CytoDyn Inc. (OTCQB: CYDY) is advancing its drug candidate toward providing a better life for HIV patients. “PRO 140 is currently one of the most advanced experimental monoclonal antibodies for HIV treatment, and CYDY believes that it will be beneficial to patients with complicating issues, such as those with single or multi-drug resistant viruses or those who have difficulty sticking to a daily drug regimen, as well as those who can’t tolerate the current therapies available due to side effects and toxicity or those with compromised organ function or complex medical requirements.”
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CytoDyn is a biotechnology company focused on the clinical development and potential commercialization of humanized monoclonal antibodies for the treatment and prevention of HIV infection. The company has one of the leading monoclonal antibodies under development for HIV infection, PRO 140, which has completed phase 2 clinical trials with demonstrated antiviral activity in man and is currently in phase 3. PRO 140 blocks the HIV co-receptor CCR5 on T cells, which prevents viral entry. Clinical trial results thus far indicate that PRO 140 does not negatively affect the normal immune functions that are mediated by CCR5. Results from seven phase 1 and phase 2 human clinical trials have shown that PRO 140 can significantly reduce viral burden in people infected with HIV. A recent phase 2b clinical trial demonstrated that PRO 140 can prevent viral escape in patients during several months of interruption from conventional drug therapy. CytoDyn intends to continue to develop PRO 140 as a therapeutic anti-viral agent in persons infected with HIV and to pursue non-HIV indications where CCR5 and its ligand CCL5 may be involved. For more information on the company, please visit www.cytodyn.com.
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