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ContraVir Pharmaceuticals, Inc. (CTRV) Shares Spike on Positive Safety Profile of CMX157

Company: ContraVir Pharmaceuticals, Inc. (CTRV)
Category: News

Shares of ContraVir Pharmaceuticals (NASDAQ: CTRV) are trading more than 28% higher in late morning trade after the company said it will pivot from a positive recommendation from an independent Data Safety Monitoring Board (DSMB) to begin enrollment of the next dosing group in its head-to-head phase 2a dose-escalation study. The study is structured to compare the safety and efficacy of ContraVir’s CMX157 to tenofovir disoproxil fumarate (TDF, marketed by Gilead Sciences as Viread®) in patients with chronic hepatitis B (HBV). ContraVir expects to complete the remaining two escalation cohorts and report top-line results by year-end 2016.

To view the full press release, visit: http://nnw.fm/r8ANM

About ContraVir Pharmaceuticals

ContraVir is a biopharmaceutical company focused on the development and commercialization of targeted antiviral therapies with a specific focus on developing a potentially curative therapy for hepatitis B virus (HBV). The Company is developing two novel anti-HBV compounds with complementary mechanisms of action: CMX157, a highly potent analog of the successful antiviral drug tenofovir currently in a Phase 2a clinical trial in HBV patients; and CRV431, a next generation cyclophilin inhibitor with a unique structure that increases its potency and selective index against HBV. ContraVir is also developing FV-100, an orally available nucleoside analogue prodrug for the treatment of herpes zoster, or shingles, in a Phase 3 clinical trial. In addition to direct antiviral activity, FV-100 previously demonstrated the potential to reduce the incidence of debilitating shingles-associated pain known as post-herpetic neuralgia (PHN) in a Phase 2 clinical study. For more information visit www.contravir.com

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