NetworkNewsBreaks – ArQule, Inc. (NASDAQ: ARQL) Shares Sink on Disappointing Liver Cancer Trial
Shares of ArQule (NASDAQ: ARQL) dropped more than 20% this morning on news that the company, along with Daiichi Sankyo Cancer Enterprise, announced that the METIV-HCC phase 3 study of tivantinib in hepatocellular carcinoma (HCC) did not meet its primary endpoint of improving overall survival. A total of 340 patients with MET-overexpressing HCC analyzed by a validated immunohistochemical assay were randomized in the intent-to-treat population for efficacy analysis. Full results from the trial will be presented at an upcoming scientific forum. “HCC is a disease with high unmet need, especially in the second-line setting, so these results are disappointing for…







