ContraFect (NASDAQ: CFRX) was featured in a recent equity research report published by Mizuho Securities USA LLC. The report reads, “ContraFect reported 2Q 2020 results and provided an update on their clinical program on Friday. We also had a chance to catch up with the company directly following the release. Most importantly, things appear to be on track for lead asset exebacase and the ongoing Phase 3 DISRUPT trial. While the COVID-19 pandemic may naturally impact the progress of the trial, they continue to expect interim data (after 60% enrollment) in 1H 2021 and final results in 2H 2021. We continue to see ContraFect as an interesting high-risk/high-reward opportunity given exebacase’s potential to become the standard of care in treating methicillin-resistant Staph aureus (‘MRSA’) infections, an area of high unmet medical need.”
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About ContraFect Corp.
ContraFect is a biotechnology company focused on discovering and developing differentiated biologic therapies for life-threatening, drug-resistant infectious diseases, particularly those treated in hospital settings. An estimated 700,000 deaths worldwide each year are attributed to antimicrobial-resistant infections. We intend to address life threatening infections using our therapeutic product candidates from our platform of DLAs, which include lysins and amurin peptides. Lysins are a new class of DLAs which are recombinantly produced antimicrobial proteins with a novel mechanism of action associated with the rapid killing of target bacteria, eradication of biofilms and synergy with conventional antibiotics. Amurin peptides are a new class of DLAs, which exhibit broad-spectrum activity against a wide range of antibiotic-resistant Gram-negative pathogens, including Pseudomonas aeruginosa (P. aeruginosa), Acinetobacter baumannii, and Enterobacter species. We believe that the properties of our lysins and amurin peptides will make them suitable for targeting antibiotic-resistant organisms, such as MRSA and P. aeruginosa, which can cause serious infections such as bacteremia, pneumonia and osteomyelitis. Our lead lysin candidate, exebacase, was granted Breakthrough Therapy designation by the FDA for the treatment of MRSA bloodstream infections (bacteremia), including right-sided endocarditis, when used in addition to standard-of-care (“SOC”) anti-staphylococcal antibiotics in adult patients. For more information, visit the company’s website at www.ContraFect.com.
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